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Related to CFTR: cystic fibrosis, CFTRI


The two-character ISO 3166 country code for CENTRAL AFRICAN REPUBLIC.


1. On a bond transaction table, an abbreviation indicating that a bond has matured, but is still trading.

2. ISO 3166-1 alpha-2 code for the Central African Republic. This is the code used in international transactions to and from Central African bank accounts.

3. ISO 3166-2 geocode for the Central African Republic. This is used as an international standard for shipping to the Central African Republic. The capital and each prefecture have their own codes with the prefix "CF." For example, the code for the Prefecture of Ouaka is ISO 3166-2:CF-UK.


Used in bond transaction tables in newspapers to indicate that the certificate of a bond has matured but is still trading: VarCp 10s99cf.
References in periodicals archive ?
CFTR Modulators for the Treatment of Cystic Fibrosis.
The most common diseases associated with CFTR are asthma.
Sequencing of additional exons and intron junctions (17, 19) and a search for CFTR genomic rearrangements (20, 21), are needed to detect possible regionally prevalent mutations and rare (private) mutations in the 53.
It has also been showed that whenever M470V polymorphism comes along with another polymorphism mutation that leads to less activation of CFTR protein function (8, 35).
The objective of this study was to evaluate our AmpliSeq custom assay (PCR-based target enrichment followed by massively parallel sequencing on the PGM) for detecting inherited CFTR mutations in the clinical laboratory setting.
CFTR expression has previously been localised to the apical membrane of the corneal endothelium, (31,33,54) where it is known to facilitate fluid efflux in order to maintain corneal transparency.
Ile1027Thr substitution in the CFTR gene is unknown and it has been reported variably as a polymorphism or a deleterious mutation.
Our findings suggest that CFTR is a multi-tasker protein that is not only involved in chloride transport but also in regulating cell death and inflammation by keeping in check the rampant and dangerous accumulation of ceramide," said principal investigator Neeraj Vij, Ph.
Although the sample size was small, this report suggests that exon copy number variants of CFTR is not a major mutational mechanism giving rise to CF in black and coloured southern African CF patients.
We used dilutions of 1:2 for CAII, 1:400 for NHE3, 1:50 for CFTR, 1:100 for DRA, 1:200 for ATPase [alpha]1, 1:400 for ER[alpha], and 1:400 for ER[beta].
Genzyme Corporation today announced the commercial availability of cystic fibrosis (CF) gene sequencing -- a new diagnostic test that can detect approximately 98 percent of the more than 1,200 disease-causing mutations in the CFTR gene.
The CFTR gene is responsible for producing glutathione, as it makes the CFTR protein that exports glutathione.