Chen et al., "Fluoxetine reduces
CES1, CES2, and CYP3A4 expression through decreasing PXR and increasing DEC1 in HepG2 cells," Xenobiotica, vol.
As the majority of clopidogrel dose is being metabolized by the
CES1 enzyme, a reduced function genetic polymorphism of this enzyme can lead to variable response to clopidogrel [23, 43].
CYP2B10, CYP3A11, CYP2F2, and
CES1, which are CAR and PXR downstream proteins, 4-hydroxyphenylpyruvate dioxygenase (HPD), glycine N-methyltransferase (GNMT), glycineN-acyltransferase (GLYAT), paraoxonase 1 (PON1), and urea cycle enzymes were also overexpressed in PB-treated [Ogg1.sup.-/-] HCCs, but not in [Ogg1.sup.+/+] HCAs (Table 2).
These 11 genes were Gbx2, KI67, CCNB1, BUB1, KNTC2, USP22, HCFC1, RNF2, ANK3, FGFR2, and
CES1. (84)
Na primeira avaliacao (nao-destrutiva), foram medidas as seguintes caracteristicas: altura de plantas (EST), comprimento de estolao primario (
CES1), utilizando uma regua graduada (cm); habito de crescimento (HAB), avaliado visualmente, sendo atribuidas notas 1, 2 e 3 para plantas prostradas, decumbentes e eretas, respectivamente; numero de folhas vivas (NFV) e senescentes (NFS), por contagem; area foliar de 3 folhas (AF), em um planimetro otico modelo LICOR 3100; e producao de massa seca da parte aerea (MSPA = folha + estolao), atraves do corte das plantas com auxilio de tesouras e secagem em estufa a 60[degrees]C ate massa constante.
Recognized dystocia scores were
CES1 = no problem, CES2 = slight problem, CES3 = needed assistance, CES4 = considerable force, CES5 = extreme difficulty.