Patients with unipolar depression usually experience loss of appetite and weight loss, whereas in our clinical experience, patients with bipolar depression
often overeat, crave carbohydrates, and gain weight.
The nature of bipolar depression
: Implications for the definition of melancholia.
Although favorable outcomes using modafinil for treatment of bipolar depression
have been reported in literature, clinicians should remain cautious of the potential to rapidly induce psychosis with modafinil at low dosages in patients with bipolar depression
despite being treated with mood stabilizers and antipsychotics.
Currently, olanzapine-fluoxetine combination (OFC), quetiapine (either the standard or the extended release preparation), and lurasidone are the only FDA drugs granted (extended) approval for the (acute) treatment of bipolar depression
in adults [20, 21].
Data were collected on the basis of a single cross-sectional interview of 30 subjects with bipolar depression
and 30 patients with unipolar depression, who attend psychiatry OPD at SMS Hospital, Jaipur and fulfilled the inclusion/exclusion criteria.
Monotherapy: LATUDA is indicated as monotherapy for the treatment of patients with major depressive episodes associated with bipolar I disorder (bipolar depression
agents, which should not be confused or used interchangeably with the term antidepressants, include effective medications for the treatment of bipolar depression
The drug has been used off-label as maintenance treatment and for bipolar depression
, both as monotherapy and in combination with other mood-stabilisers and 2nd generation antipsychotics .
Among the topics are theories of what causes depression, dealing with the health care system and insurance, choosing an antidepressant for major depressive disorder, the different approaches required for bipolar depression
, child and adolescent depression, extreme measures such aselectroconvulsive therapy and repetitive transcranial magneticstimulation, complementary and alternative medicine and living a healthy life with a psychiatric illness.
A new study suggests that a 50-year-old drug commonly used as an anesthetic for humans and animals--and abused as the drug called "Special K"--may deliver almost instant relief in some of the most troublesome cases of bipolar depression
. It has been known for several years that small doses of the drug, ketamine, can relieve major depression.
Aware of the critical need for antidepression treatments that might not carry the risk of precipitating a manic episode in bipolar patients, we decided to conduct an open-label add-on trial of eicosapentaenoic acid (EPA) in bipolar depression
. METHOD: Twelve bipolar I outpatients with depressive symptoms diagnosed by DSM-IV were treated with 1.5 to 2 g/day of the omega-3 fatty acid EPA for up to 6 months.
Richard Maddison, who suffers from bipolar depression
, said the drugs were for his own use and helped calm him down.