The Binding Site
leases laboratories from the university and does much of its work there.
It is notable that a 200-bp region immediately upstream of the transcription start site contained highly conserved transcription factor-binding motifs, including the Oct4/Sox2 binding site
and Sp1 binding motifs.
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where Vcell is the volume of calorimeter cell, i is the increment of binding ratio from injection j-1to j and Hi is the binding enthalpy of i class of binding site
Analysis of the Binding Site
between the Aptamers and the Protein
This enables it to poke into the site without touching the rest of the binding site
," Wilson explains.
In an effort to locate the C9 binding site
on C8[alpha], truncated and chimeric C8[alpha] in which modules were deleted or exchanged for those in C8[beta] were expressed independently or as heterodimers with C8[gamma] and combined with C8[beta].
The three-dimensional structure of DAT is not known, but the current findings suggest that TMs 1-2 and 4-6 are in close proximity and encompass at least part of the binding site
for these two classes of uptake blockers.
The natural enzyme is stabilized in part by the presence of bound calcium at two different sites, a high-affinity site (site A) and a weaker less specific binding site
We searched the available gene sequence for a hexanucleotide element (5'-ACGTGC-3') representing the consensus HIF-l binding site
That site has been described as the PCP binding site
and PCP binding inhibits the potential excitotoxic actions of endogenous agents like glutamate.