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When compared to urine ketone analysis, serum beta-hydroxybutyrate measurements have proven at least as--if not more--sensitive in the setting of diabetic ketoacidosis.
One paper has established guidelines in which the resolution of the metabolic derangements in diabetic ketoacidosis can be followed by serum beta-hydroxybutyrate levels.
Capillary blood beta-hydroxybutyrate measurement by reagent strip in diagnosing diabetic ketoacidosis.
Plasma and milk glucose or plasma beta-hydroxybutyrate levels were not affected by DFM.
Ketosis was measured by whole blood levels of beta-hydroxybutyrate (BHB).

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