BIS

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BIS

Bank for International Settlements

An international organization composed of central banks that helps ensure the proper flow of money throughout the global economy. Based in Basel, Switzerland, the BIS seeks to increase transparency in monetary policy throughout the world, and to apply international standards where it is believed they are appropriate. The BIS regulates capital adequacy and encourages transparency in reserve requirement policies. Importantly, it does not provide financial aid to members. Critics allege that its standards are unenforceable. See also: International Monetary Fund.

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Proceeds from the series A financing will be used to advance the company's first-of-its-kind gene replacement therapy through filing of an IND in preparation to initiate human clinical trials in DCM patients who have mutations in their BAG3 gene.

Renovacor Closes USD 11m series A Financing to Advance First Gene Therapy for a Rare Cardiovascular Disease

Khalili et al., "BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy," The American Journal of Pathology, vol.

Combination Treatment with PPAR[gamma] Ligand and Its Specific Inhibitor GW9662 Downregulates BIS and 14-3-3 Gamma, Inhibiting Stem-Like Properties in Glioblastoma Cells

The first, Bag3, a prooncoprotein, is involved in the mitochondrial stress response and disease [47, 48].

The aryl-hydrocarbon receptor protein interaction network (AHR-PIN) as identified by tandem affinity purification (TAP) and mass spectrometry

[9] Human genes: SORT1, sortilin 1; BAG3, BCL2-associated athanogene 3; LIPA, lipase A; CYP2C9, cytochrome P450, family 2, subfamily C, polypeptide 9; VKORC1, vitamin K epoxide reductase complex, subunit 1.

Next steps in cardiovascular disease genomic research--sequencing, epigenetics, and transcriptomics

The antitumor effects of miR-143 were related to BAG3 expression in GSC cells [87].

Review of Natural Product-Derived Compounds as Potent Antiglioblastoma Drugs

[3] Human genes: USP3, ubiquitin specific peptidase 3; HSPB7, heat shock 27kDa protein family, member 7 (cardiovascular); BAG3, BCL2-associated athanogene 3; APOE, apolipoprotein E; SORT1, sortilin 1.

Heritability, weak effects, and rare variants in genomewide association studies

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