grew longer and straighter on stiff surfaces and seemed to meander more on softer material.
In mature axons
the microtubule cytoskeleton is stably maintained, but after axonal injury it is transformed in a highly dynamic state.
After spinal cord injury, axons
try to cross the injury site and reconnect with other cells but are stymied by scarring that forms after the injury.
The MLF neurones started projecting axons
caudally at stage 19 (Figure 1(b), e).
We also traced descending corticospinal tracts with an axon
tracer in these SCI animals and found a greater number of axons
to grow into the scar tissues, although a small number of corticospinal axons
were detected in the caudal spinal cord.
We discovered that VEGF is able to attract nervous system axons
Activity in the vpn was seen only from these two large axon
pairs and two much smaller axons
during about 20 h of recording from the L.
Paradoxically, a surplus of oligodendrocytes early in brain development may lead to a dearth later, because if there are proportionally fewer neurons, many oligodendrocytes cannot wrap an axon
Also important are neurotrophic factors, often provided by glial cells, other axons
, and glycoproteins located throughout the brain.
On electron microscopy, distinct abnormalities were observed in the myelination of axons
with the vestibular nerves; the most common abnormalities were cleavage, splitting, and fragmentation of the myelin lamellae (figures 2, A, and 2, B).
Within the spinal cord, the axons
and cell bodies of spinal cord neurons occupy different regions.
They are well known to stimulate axon
regeneration by making proteins that promote nerve growth either on contact, or at a distance (by secreting growth factors).