Clinical significance of atypical glandular cells
on cervical cytology.
In our population, abnormal pap tests were most closely associated with ASCUS, followed by LGSIL, HGSIL, atypical glandular cells
, and ASC-H (Table 2).
atypical squamous cells-cannot rule out H-SIL AGUS, atypical glandular cells
of undetermined lesions H-SIL, high grade squemous intraepithelial lesions L-SIL, low grade squemous intraepithelial lesions Table III.
Out of 27 cases of epithelial cell abnormality are of atypical squamous cells of undetermined significance (ASCUS) (17), atypical glandular cells
of undetermined significance (AGCUS) (1), low-grade squamous intraepithelial lesion (LSIL) (2), high-grade squamous intraepithelial lesion (HSIL) (2) and invasive carcinoma cervix (5).
Guidelines from the 2001 Bethesda system suggested, in addition to reporting of atypical glandular cells
(AGC) and adenocarcinoma, the reporting of benign appearing endometrial cells in women aged above 40 years is mandatory and a review of literature supports this recommendation.
There are two categories of ambiguous pathological lesions, namely ASCUS (atypical squamous cells of undetermined significance) and AGUS (atypical glandular cells
of undetermined significance).
Cheng WE, Chen YL, You SL, et aL Risk of gynaecological malignancies in cytologically atypical glandular cells
: follow-up study of a nationwide screening population.
Minor changes are seen in the management of atypical glandular cells
and abnormal cervical cells in pregnant women.
"Adenocarcinoma insitu" (AIS) would become a distinct entity, and "atypical glandular cells
of undetermined significance" (AGUS) would be renamed to eliminate confusion with ASCUS.