Management of atypical glandular cells
and adenocarcinoma in situ.
The utility of human papillomavirus testing in young women with atypical glandular cells
on Pap test.
NILM: negative for intraepithelial lesion and malignancy; ASC-US: atypical squamous cells of undetermined significance; ASC-H: atypical squamous cells, cannot exclude high-grade lesion; LSIL: low-grade squamous intraepithelial lesion; HSIL: high-grade squamous intraepithelial lesion; AG: atypical glandular cells
; AG-NOS: atypical glandular cells
not otherwise specified.
Abnormal cervical cytology distribution Cytology result Frequency Percent ASC-H 5 3 ASCUS 103 62 Atypical glandular cells
6 4 HGSIL 8 5 LGSIL 44 27 Total 166 100 Table 3.
found approximately one-third of women with a diagnosis of atypical glandular cells
of endometrial origin had a significant uterine lesion on subsequent biopsy and suggested that Patients with a diagnosis of atypical endometrial cells on cervicovaginal smears should be followed closely, and endometrial curettage or biopsy should be included in their initial work-up.
AGC-US: Atypical Glandular Cells
of Undetermined Significance.
Key words: atypical glandular cells
, squamous intraepithelial lesions, endocervical curettage, colposcopy.
Human Papilloma Virus, Atypical Glandular Cells
, cervical smear.
Out of 27 cases of epithelial cell abnormality are of atypical squamous cells of undetermined significance (ASCUS) (17), atypical glandular cells
of undetermined significance (AGCUS) (1), low-grade squamous intraepithelial lesion (LSIL) (2), high-grade squamous intraepithelial lesion (HSIL) (2) and invasive carcinoma cervix (5).
We assigned a stepwise discordance score in those cases that had a Pap test within 5 years of tissue diagnosis: a score of 0 was assigned for atypical glandular cells
(AGC)-favor neoplasia and above or for cytology specimens called high-grade SIL (HSIL) if histologic HSIL (cervical intraepithelial neoplasia 2/3) was also present in the tissue biopsy, a score of 1 was assigned for AGC not otherwise specified or if the cytology specimen was called HSIL and histologic HSIL was not present in the tissue biopsy, a score of 2 was given for cytology samples called low-grade SIL (LSIL), a score of 3 for ASCUS, and a score of 4 for negative for intraepithelial lesion or malignancy (NILM).
Adhere to 2006 ASCCP guidelines for the management of women who have a cytologic finding of atypical glandular cells