wd

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Related to ATP7B: ceruloplasmin

When Issued

Referring to a conditional offer for a new security, subject to the security actually being issued. Before a new issue, underwriters canvass potential investors, who may or may not book an order to buy a portion the new issue. Orders made are said to be effective "when issued" because they may not be completed, especially if the offering is cancelled. Less formally, orders when issued are referred to as orders "with ice" or orders "when distributed."

WD

Used on the consolidated tape to indicate that a stock is trading on a when-distributed basis: GY.WD 52.

wd

Used in stock and bond transaction tables in newspapers to indicate that a security is trading on a when-distributed basis: ColgP wd.
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References in periodicals archive ?
La EW es un trastorno metabolico del transporte celular del Cu, autosomico recesivo, causado por mutaciones en el gen ATP7B en el cromosoma 13 (13q14.3), el cual codifica una ATPasa transportadora de Cu ligada a la membrana de los hepatocitos, la cual es requerida para la incorporacion del Cu en la apoceruloplasmina para ser transformada en ceruloplasmina, a su vez esta proteina es necesaria para liberar la ceruloplasmina a la circulacion y la excrecion del Cu a traves de la bilis (1,2,4).
Wilson's disease, an autosomal recessive disorder is characterized by a mutated ATP7B enzyme [1-14].
Heneka, "Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease," Journal of Neurochemistry, vol.
In a study of four pregnancies where both parents were Wilson disease carriers, the team demonstrated that cSMART can diagnose Wilson disease if the sequences of the parents' mutant ATP7B variants are known.
Familial pathogenic mutations were identified in ATP7B by Sanger and whole-exome sequencing.
A growing body of data suggests that COMMD1 is associated with a multimeric E3 ubiquitin ligase complex and regulates the stability of proteins such as NF-[kappa]B subunits, ATP7B, and HIF-1-[alpha] [7-11].
Loss of the Cu transporter ATP7B in Wilson's disease model mice presents as elevated brain copper, neurodegeneration, and inflammation [128].
Wilson hastaliginda (hepatolentikuler dejenerasyon), karacigerde bakir tasiyici enzim (ATP7B) defekti nedeniyle safra kesesinden bakir atiliminda azalma ve karaciger, bobrek, beyin ve korneada bakir birikimi ile giden otozomal resesif gecisli bir metabolik hastaliktir.
(12) Esta proteina no tiene expresion en el higado, donde la ATP7B o proteina de Wilson se expresa mayoritariamente; esta proteina comparte un 67% (7) de aminoacidos con la proteina de Menkes.
kromozom uzerindeki ATP7B (ATPase, [Cu.sup.++] transporting, beta polypeptide) geni (13g14.3-g21.1) etkilenmistir.