Threshold

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Threshold

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Anticonvulsant medications, which are commonly used in the psychiatric patient, act to raise the seizure threshold and decrease the length of the seizure.
They are thought to increase the seizure threshold by either directly modifying cell membrane function or altering chemically mediated neurotransmission.
Low-dose unilateral ECT creates even fewer memory deficits, but may fail to relieve depression because "different regions in the right hemisphere probably have different seizure thresholds," says Sackeim.
Therefore, although EEG readings were not recorded during induction of anaesthesia, in view of the clinical observations and the literature described above, we suggest that the tonic-clonic movements observed in the patient's left upper limb resulted from seizure activity triggered by sevoflurane because of a lowered seizure threshold, secondary to the previous hypocalcaemia-induced focal seizure activity.
There is no scientific evidence suggesting that exercise lowers seizure threshold or alters anti-epileptic drug levels,[17] but clinical data suggest seizure incidence is actually reduced during participation in sports and exercise.
5 times the seizure threshold for bifrontal and bitemporal placements and 6 times the threshold for right unilateral electrode placement.
Drugs such as theophylline lower the seizure threshold.
Or does the low seizure threshold of temporal lobe structures as well as their connections with sensory, motor and limbic systems, help explain the ubiquitous contribution of this region to seizure activity?
The electrical stimulation increases the seizure threshold and reduces the occurrence of seizures.
Estrogen enhances neuronal excitability and lowers the seizure threshold, whereas progesterone decreases excitability and raises the seizure threshold.
There are several neurotransmitter changes with age: some that increase the seizure threshold and some that decrease it.
Under current Food and Drug Administration guidelines, ECT devices are not capable of administering six times the seizure threshold dosing to all patients, because some individuals constitutionally have high seizure thresholds.