Clearance

(redirected from mucociliary clearance)
Also found in: Dictionary, Thesaurus, Medical, Legal, Acronyms, Encyclopedia, Wikipedia.
Related to mucociliary clearance: mucociliary clearance rate

Clearance

The process of settling transactions. Most exchanges have one or more clearing houses, which are charged with matching orders together, ensuring that deliveries are made to the correct parties, and collecting margin money. Because so many trades take place on an exchange in a given day, clearing houses exist to process what each party owes or is owed in a central location so the fewest securities actually change hands. For example, suppose that a broker-dealer buys 1000 shares of a security and then, in a completely separate transaction, sells 700 of the same shares. At the end of the trading day, the clearing house would determine that the broker-dealer must only buy 300 shares as the other 700 belong to another party. Clearing houses receive a clearing fee in exchange for clearance services.

Clearance.

Clearance is the first half of the process that completes your order to buy or sell a security. During clearance, the details on both sides of the transaction are compared electronically to ensure that the order to buy and the order to sell correspond.

For example, in a stock transaction, the Committee on Uniform Securities Identification Procedures (CUSIP) number, the number of shares, and the price per share must match.

Next, transactions within each broker-dealer are netted down, or offset, by matching its clients' buy orders against sell orders from others of its clients or among a group of affiliated firms. Their records are then updated to reflect the new ownership and account balances.

Any unmatched orders are forwarded to the National Securities Clearing Corporation (NSCC), which instructs selling broker-dealers to provide the relevant securities and the buying broker-dealer to send the cash.

References in periodicals archive ?
The effect of a temporary nasoantral window on mucociliary clearance.
Some studies have shown that they exert beneficial effects on nasal physiology, mucociliary clearance in particular, (15-18) and that they help relieve symptoms and improve quality of life in patients with sinonasal disease.
Denufosol is designed to enhance the lung's innate mucosal hydration and mucociliary clearance mechanisms, which in CF patients are impaired due to a genetic defect.
discovers and develops new drugs to treat diseases characterized by deficiencies in the body's innate defense mechanisms of mucosal hydration and mucociliary clearance, as well as other non-mucosal disorders.
The remaining mucosa of the maxillary sinus was preserved to allow for functional mucociliary clearance through the antrostomy opening.
Cystic fibrosis is a life-threatening disease involving a genetic mutation that disrupts the cystic fibrosis transmembrane regulator (CFTR) protein, resulting in poorly hydrated, thickened mucous secretions in the lungs, as well as severely impaired mucociliary clearance.
discovers, develops and commercializes new drugs to treat diseases characterized by deficiencies in the body's innate defense mechanisms of mucosal hydration and mucociliary clearance, as well as other non-mucosal disorders.
1) According to the Messerklinger approach, the key to eliminating persistent sinus infection is to re-establish physiologic mucociliary clearance patterns.
The single-dose trial is designed as a double-blind, two-way crossover evaluation of the effects of 60 mg of denufosol on mucociliary clearance, compared to placebo, in 12 patients with CF lung disease.
Mucosal hydration involves the moistening of the body's mucosal surfaces, and mucociliary clearance involves a blanket-like movement of fluid and particles from the lungs and sinuses.
13) Mucociliary clearance can be monitored by analyzing ciliary beat frequency with in vitro testing.
Denufosol tetrasodium is a selective P2Y2 agonist designed to enhance the lung's innate mucosal hydration and mucociliary clearance mechanisms by activating an alternative ion channel that acts in the same way as the defective ion channel normally would in moving salt and water to the surface of the airways.