Icagen services focus on ion channel
and transporter drug discovery and development, harnessing its industry leading scientific expertise and extensive portfolio of assays, cell lines and technologies including its proprietary, XRpro label free technology.
Qube is a 384-channel automatic patch clamp system that delivers ion channel
data at an unprecedented throughput.
The lab of Kevin Foskett at the University of Pennsylvania School of Medicine explored the role of CFTR, the chloride ion channel
mutated in CF patients, in fluid secretion by mucous gland cells.
Waxman and others led to development of treatments that might improve neurological function in MS by altering ion channel
Integral Molecular's Lipoparticles enable ion channels
such as M2, and other membrane proteins, to be selectively captured and concentrated.
The glutamate binds inside the clamshell and the ion channel
opens, the researchers report.
HIV-I gp120 and chemokines activate ion channels
in primary macrophages through CCR5 and CXCR4 stimulation.
Tom has held a range of management positions at Molecular Devices, Becton Dickinson, and has a history of successful product launches in the cell analysis and ion channel
Impending Patent Expiries of Select Ion Channel
Brown collaborates with the US Federal Drug Administration (FDA) on cardiac safety issues and he holds nine patents on ion channel
pharmacology, therapeutics and devices.
Julius' group had previously shown that capsaicin, the compound that gives chili peppers their spicy kick, activates a different but related ion channel
(SN: 11/8/97, p.
Combination with IonFlux[TM] Automated Patch Clamp System creates a validated, affordable solution for ion channel
profiling and screening