Krammer F, Margine I, Tan GS, Pica N, Krause JC, Palese P A carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin
The Mycobacterial heparin-binding hemagglutinin
is a protective antigen in the mouse aerosol challenge model of tuberculosis.
The first fraction collected represented purified hemagglutinin
Prediction of mutation trend in hemagglutinins
and neuraminidases from influenza A viruses by means of cross-impact analysis.
gene of this virus was distantly related to those of H5N1 subtypes that have caused infections in humans since 1997 (3).
Influenza A viruses can be subdivided on the basis of antigenicity of its surface glycoproteins neuraminidase and hemagglutinin
is disabled, the virus is locked out and can't infect cells.
One common mutation that helps viruses do that, called Q226L, changes an amino acid in the hemagglutinin
protein, the molecule that gives the virus the H in its name.
The four influenza vaccines licensed by the Food and Drug Administration over the past year are two quadrivalent vaccines that include two influenza B strains and two influenza A strains; a cell-culture-based vaccine; and an egg-free, recombinant hemagglutinin
vaccine manufactured without the use of influenza viruses.
Of the 24 AIVs, 16 subtypes were detected, representing nine hemagglutinin
and seven neuraminidase subtypes.
The mutation comprised of alterations in the Hemagglutinin
protein which allows the virus to infect new hosts.
one or more of influenza hemagglutinin
, influenza nuclear protein, tetanus toxin C-fragment, anthrax protective antigen, HIV gp 120, human carcinoembryonic antigen, and/or a therapeutic, an immunomodulatory gene, such as co-stimulatory gene and/or a cytokine gene.