The researchers found that a higher genetic risk
score significantly increased the incidence of coronary events as much as 90 per cent in those at highest risk.
This points to a significant genetic risk
, but the role of environmental factors is also substantial.
They constructed a mulilocus genetic risk
score for each individual by summing the number of risk alleles for each of the 13 SNP weighted by effect size.
In recent years there has been a dramatic increase in the discovery of information related to the genetic risk
of disease, as well as in the technical ability to accurately measure an individual's genotype.
Scientists examined the effect of offering screening to women based on their genetic risk
as well as age.
The company's Web site promised that, in return, I would get genetic risk
information that would allow me to "make lifestyle choices" and "make more informed decisions" about my health--in other words, personalize my health behaviors and medical care.
Can we do anything to stop children at genetic risk
from developing mental illness?
After adjusting for traditional heart disease factors, such as blood pressure and total cholesterol, the genetic risk
score was not associated with heart disease risk.
A trio of genome-wide studies -- collectively the largest to date -- have pinpointed a vast array of genetic variation that cumulatively may account for at least one third of the genetic risk
An article recently published in the British Journal of Ophthalmology identified a new genetic risk
factor for AMD.
Working with mice bred to possess genetic risk
factors for the development of dementia, investigators noted that these mice developed oxidative damage leading to cognitive impairment when deprived of the B-vitamin, folic acid.
After what has been described as the most comprehensive examination ever of the genetic risk
factors for type 2 diabetes, researchers have identified at least four new genetic variants associated with an increased risk of diabetes while confirming the existence of six others.