Nexus

(redirected from gap junction)
Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia, Wikipedia.

Nexus (of contracts)

A set or collection of something.

Nexus of Contracts

Any contract or other thing that is related to anything else, especially something that causes something else.
References in periodicals archive ?
Changes in expression of connexin 43 gap junction messenger ribonucleic acid and protein during ovarian follicular growth.
Heterogeneity of gap junction distribution combined with reduced Cx43 levels appear to act co-operatively to create an arrhythymogenic substrate.
The basal cells are joined by gap junctions to intermediate cells and to fibrocytes of adjacent connective tissue, indicating exchanges between these three cell types.
ECM and gap junctions play important roles during the development of follicle cells, but up to now, the effect of PG's precursor-AA on ECM, gap junctions and follicle development is still unclear.
The factors involved in the structural, gap junction and ion channel remodeling are mutually interrelated and it is suggested that the passive myocardial structure has a major effect on the role of membrane currents in the propagation of the action potential.
PharmaGap was founded in 1999, ten years after the original Christmas discovery, and the small biotech company continues to unwrap the mysteries of gap junction modulation.
Incompatibility of connexin 40 and 43 hemichannels in gap junctions between mammalian cells is determined by intracellular domains.
The researchers investigated an approach that targets a liver's gap junctions - hollow multimolecular channels that connect neighboring cells and allow direct communication between coupled cells.
In recent study, carbenoxolone (as a gap junction blocker), in the in vitro ischemic model, significantly decreased the spread of cell death during ischemic episode and impairment of intrinsic neuronal activities using electrophysiological recording (Frantseva et al.
Therefore, in subsequent experiments we exposed cardiac myocytes to concentrations of Zn and V similar to those used in the beat rate experiments to determine whether these metals also produce dissimilar effects on ion channel, gap junction protein, and inflammatory mediator mRNA accumulation.
Gap junctions are very common in invertebrates but rare in mammals, where they are found on only certain inhibitory interneurons.
Pipeline candidates fall under major therapeutic classes such as factor Xa inhibitors, direct thrombin inhibitors, and gap junction modifiers, along with other novel anti-arrhythmic drugs.