Toxin

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Related to exfoliative toxin: Staph aureus

Toxin

Any poisonous substance a living thing produces as part of its metabolic or other natural process. That is, toxins themselves are not living things, but are produced by living things. Toxins are defined by the Biological Weapons Convention.
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Rapid and specific detection of toxigenic Staphylococcus aureus: use of two multiplex PCR enzyme immunoassays for amplification and hybridization of staphylococcal enterotoxin genes, exfoliative toxin genes, and toxic shock syndrome toxin 1 gene.
The strain had an agr type 1 allele and the lukS-PV/lukF-PV genes encoding PVL (Figure), but harbored no toxin genes (sea through see, tsst, eta, and etb genes encoding staphylococcal enterotoxins A though E, toxic shock syndrome toxin, and exfoliative toxins A and B, respectively).
These strains were sent to the French Reference Center for Staphylococci, where genetic sequences encoding accessory gene regulator (agr) subtypes, enterotoxins, exfoliative toxins, toxic-shock syndrome toxin-1, hemolysins, and LukE-LukD leukotoxin were detected by polymerase chain reaction (PCR)-based methods.