Disposition

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Disposition

The sale of a security. See also: Close a position.
References in periodicals archive ?
Additionally, effects on drug disposition can last for a few days after consuming a grapefruit product.
In addition, nadolol is classified as a class III drug in BCS and also Biopharmaceutics Drug Disposition Classification System (BDDCS), characterized by high solubility, low permeability and poor metabolism (Wu and Benet 2005; Yang et al.
Genetic and environmental factors affecting drug disposition in man.
The chapter on Pharmacogenomics by the third contributor (Anahita Bhathena), is an excellent summary of where we are in a number of areas, and includes the pharmacokinetics of drug disposition and even tables of useful Web sites.
Busulfan PK studies have demonstrated wide intra- and interpatient variation in drug disposition, metabolism, and clearance.
Sections cover approaching drug-nutrient interactions; the influence of nutritional status on drug disposition and effect; the influence of food, nutrients, and supplementation on drug disposition and effect; the influence of medication on nutrition status, nutrient disposition, and effect; drug-nutrient interactions by life stage; and drug-nutrient interactions in specific conditions.
For those variant proteins that do alter drug disposition or response, if they can be uncovered a priori, that knowledge should help predict drug response.
MDR1 encodes P-glycoprotein, a key protein involved in drug transport that is known to modulate drug disposition.
For some drugs or classes of drugs, genetic factors can account for up to 95% of inter-individual variability in drug disposition and effects.
1 Regulatory Drug Disposition and NDA Package Including MIST

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