We conducted a prospective study of 60 patients in a tertiary care referral center to ascertain the status of cell-mediated immunity as determined by delayed hypersensitivity reactions
in patients with nasopharyngeal carcinoma (NPC) or allergic rhinitis.
Macrophage are responsive to a number of lymphokines that induce their growth differentiation and activation; since lymphokines are released by primed lymphocytes, produced chiefly by T-lymphocytes, on contact with an antigen , and the demonstration of a lymphookine mediated reaction in this study strongly supported the existence of T like lymphocytes in Tilapias and that the fish is capable of delayed hypersensitivity reactions
2), (3) For those with food allergies that are not IgE-mediated and associated with delayed hypersensitivity reactions
, estimates are more difficult to determine.