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| Because a delayed hypersensitivity reaction to a previously sensitized antigen occurs, patients who had not been previously vaccinated with bacille Calmette-Guerin (BCG) were not eligible for this study. The immunopathogenesis of food allergies may be governed by more than one immunologic mechanism, including immediate manifestations mediated by IgE; inflammatory reactions caused by immune complexes, lectins, and superantigens; and delayed hypersensitivity reactions associated with specific T lymphocytes (Helm and Burks 2000). Delayed hypersensitivity reaction to topical aminoglycosides in patients undergoing middle ear surgery. |
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