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half-life
(redirected from biologic half-life)

    Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
Half-life
The point in the life of a mortgage-backed security guaranteed or issued by the Government National Mortgage Association, the Federal National Mortgage Association or the Federal Home Loan Mortgage Corporation when half the principal has been repaid.
half-life
The length of time before half the principal on a debt is expected to be repaid through amortization or sinking fund payments. For example, a 25-year bond issue may require the issuer to retire 5% of the beginning principal commencing 5 years after the issue date. Thus, the bond issue has a half-life of 5 years plus the number of years required to retire half the issue, or 15 years. Mortgage-backed securities often have a relatively short half-life because many homeowners pay off or refinance their mortgages early. Also called average life.


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While the biologic half-life of methadone can range from 18 to almost 100 hours (average, about 24 hours), the analgesic half-life ranges from 6 to 12 hours.
Methadone is complex choice for managing pain by Wachter, Kerri / Clinical Psychiatry News
1) Triamcinolone acetonide is considered an intermediate-acting steroid with a biologic half-life of 18 to 36 hours (2) and is available in suspension form, which provides an increased duration of action.
A case of skin hypopigmentation secondary to a corticosteroid ... by Jones, Melissa C. / Southern Medical Journal
designed study with significant changes in the exposure for the route/pathway of interest, b) short biologic half-life of the selected chemical, and c)
Use of pharmacokinetic modeling to design studies for ... by Melnyk, Lisa Jo / Environmental Health Perspectives
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