The preferred ligands of the mu receptor are beta-endorphin
and enkephalin, those of the delta receptor are the leu- and met-enkephalines, and dynorphins A and B are those preferred by kappa receptors.
Ethanol induces apoptotic death of beta-endorphin
neurons in the rat hypothalamus by a TGF-beta 1-dependent mechanism.
Blocking the effects of beta-endorphin
with naloxone, the same drug used to treat heroin overdoses, also blocked the boost in the mice's pain threshold, the researchers found.
Maternal plasma concentrations of CRH and beta-endorphin
were seen to have a correlated rise during labour which was thought to be a response to pain perception (Mauri et al.
Hormone Function Oxytocins Uterotonic effect Antianxiolytic impact Facilitates the expression of maternal behaviour Promotes the trust levels Helps improve the memory for facial identity Beta-endorphin
Natural pain killer Decreases stress Makes the baby alert Boosts the maternal-child bond Induces bond between the partners Catecholamines Triggers survival behaviours (adrenalin, Decreases psychological distress noradrenalin) Creates energy boost Triggers the foetus ejection reflex Creates maternal-child bond Prostaglandins Makes effective uterine contractions Facilitates cervical ripening and dilatation Prolactin Regulates maternal behaviours Contributes to the direct paternal care Decreases the level of anxiety and stress Table 2.
High levels of beta-endorphin
in hypophyseal portal blood.
In these individuals, food triggers the release of dopamine and beta-endorphin
within the nucleus accumbens and ventral tegmental area.
, Metenkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis.
Characterization of the effects of acute ethanol administration on the release of beta-endorphin
peptides by the rat hypothalamus.
The Additive Synthesis of a Regulatory Peptide in Vivo: The Administration of a Vaccinal Francisella tularensis Strain That Produces Beta-Endorphin
," Biull Eksp Biol Med, August 1993.
The main groups of opioid peptides, enkephalins, dynorphins and beta-endorphin
, are derived from proenkephalin, prodynorphin and proopiomelanocortin, respectively (20).
and stress hormones in patients affected by osteoarthritis undergoing thermal mud therapy.