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| The alarm reaction or ‘fight-or-flight' response is initiated by the autonomic nervous system and the adrenal medulla or central part of the adrenal gland, which produces adrenaline and noradrenaline (also known as epinephrine and norepinephrine). It should be emphasized that the alarm reaction is not necessarily a pathologic phenomenon" (Selye, 1946, p. The opioid addict's brain has been conditioned to have an alarm reaction at the first sign of any physical pain or discomfort--which always occurs even after a short-term inpatient |
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