Combined use of pleural adenosine deaminase
with lymphocyte neutrophil ratio.
Serum adenosine deaminase
activities during acute attacks and attack-free periods of familial Mediterranean fever.
Cerebrospinal fluid Adenosine Deaminase
activity in tuberculosis meningitis.
A reduced nicotinamide adenine dinucleotide-linked kinetic assay for adenosine deaminase
Identification of a point mutation resulting in a heat-labile adenosine deaminase
(ADA) in two unrelated children with partial ADA deficiency.
One microgram of adenosine deaminase
(ADA) was then added, and the reaction was incubated at 37 [degrees]C for 10 min to remove residual dATP and then heated to 90 [degrees]C for 3 min to inactivate ADA activity.
In Japan, Hokkaido University and Kumamoto University have so far received approval to conduct gene therapy on a patient with adenosine deaminase
deficiency, which is thought to lead to immunodeficiency, and an HIV-infected patient, respectively.
The other research proposal involves the long-awaited gene-therapy trial for up to 10 children with an inherited immune disorder called adenosine deaminase
deficiency (SN: 6/16/90, p.
Researchers enhance gene therapy approach for children with adenosine deaminase
(ADA)-deficient severe combined immunodeficiency (SCID) using chemotherapy as conditioning regimen
Orphan Europe works with the following diseases: acute porphyria, congenital sucrase-isomaltase deficiency, homocystinuria, hyperammonaemia due to NAGS deficiency, nephropathic cystinosis, patent ductus arteriosus, severe combined immunodeficiency - adenosine deaminase
deficiency, vitamin E deficiency in chronic cholestasis and Wilson's disease.
3 TBq/mmol) from NEN; adenosine, AMP, ADP, ATP, cAMP, adenosine deaminase
, nucleoside phosphorylase, and xanthine oxidase from Boehringer Mannheim Germany; SAH, adenine, 2'-deoxyadenosine, L-homocysteine, diadenosine diphosphate, [N.
The project must clear other regulatory hurdles, but federal scientists say they may begin treating three or four children with adenosine deaminase
deficiency as early as this fall.