Doctors have known about this relationship for some time, but there has been very little research into why
variability increases risk.
High heart rate
variability shows that the heart is able to adapt to these changes.
Tingting Du, from the Huazhong University of Science and Technology in Wuhan, China, and colleagues evaluated whether or not intraindividual cardiovascular risk factor
variability during childhood or adolescence is an independent predictor of later-life diabetes (mean follow-up, 20.5 years).
A high-resolution (0.11[degrees]) RCM large ensemble--the Canadian Regional Climate Model (CRCM5) Large Ensemble (CRCM5-LE)--was produced to study the effects of natural climate
variability on hydrology and other local impacts.
Hence prevention of future cardiovascular events can be done by minimizing glycaemic
variability. This article focuses on its various causes, its adverse impacts and briefly discusses various newer treatment options to reduce glycaemic
variability.
Cardio scan premier 12 lux software was used for analysis of heart rate
variability frequency domain parameters.
"
Variability in metabolic parameters may be prognostic surrogate markers for predicting mortality and cardiovascular outcomes," wrote senior author Seung-Hwan Lee, MD, PhD, and professor of endocrinology at the College of Medicine of the Catholic University of Korea in Seoul, South Korea, and colleagues.
For the highest quartile in systolic BP
variability, compared with the lowest, the risk of all-cause mortality increased by 19% (HR, 1.19; 95% CI, 1.16-1.22), MI by 7% (HR, 1.07; 95% CI, 1.03-1.11), and stroke by 14% (HR, 1.14; 95% CI, 1.10-1.18).
While other measures of
variability exist, such as autocorrelations (Maes, 2003), conditional probability (Machado, 1992; Stokes, 1995), and Markov chain analysis (Machado, 1992, 1993, 1997), U-value has been most commonly used in studies to assess the level of
variability in responses where frequencies of the responses or response categories can be measured (e.g., Denney & Neuringer, 1998; Doolan & Bizo, 2013; Grunow & Neuringer, 2002; Hopkinson & Neuringer, 2003; Maes, 2003; Murray & Healy, 2013; Neuringer, 2002; Neuringer & Huntley, 1991; Page & Neuringer, 1985; Ross & Neuringer, 2002; Souza, Abreu-Rodrigues, & Baumann, 2010; Stokes 1995; Ward, Kynaston, Bailey, & Odum, 2008).
The heart is not a metronome and its beats lack the regularity of a clock, thus HR changes defined as heart rate
variability (HRV) are normal.