This intravascular haemolysis results in free Hb and
red cell debris in the general circulation.
Unfortunately, her condition subsequently deteriorated with increasing breathlessness due to a combination of pulmonary emboli, fluid overload, worsening anaemia requiring 3 further
red cell transfusions and she died 4 weeks later from pneumonia.
In regenerative anemia, she explains, the red blood cells are reduced in number as the result of acute or chronic bleeding or, less commonly,
red cell destruction within a cat's body.
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Table-2: Correlations between
red cell distribution width (RDW) and clinical and laboratory parameters.
The surface of the
red cell membrane contains genetically determined antigens, called agglutinogens, while plasma contains antibodies called agglutinins.
Band 3, the
red cell anion exchanger 1 (AE1), passes through the lipid bilayer 14 times.
The differentiation between the inclusions found in this film and other more well documented
red cell inclusions was solely based on the morphological characteristics.
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In neonates presenting with hyperbilirubinaemia, nonimmune haemolysis and a positive family history, a high index of suspicion is raised for hereditary
red cell membrane disorders.
The
red cell membrane-bound [Na.sup.+][K.sup.+]ATPase play a principal role in the regulation of intra- and extra-cellular cationic homeostasis.