Comparison of
granulocyte colony-stimulating factor (G-CSF)-mobilized peripheral blood progenitor cells and G-CSF - stimulated bone marrow as a source of stem cells in HLA-matched sibling transplantation.
Prevention of left ventricular remodelling with G-CSF after acute myocardial infarction: Final one-year results of the FIRSTLINE-AMI trial (Front-integrated revascularization and stem cell liberation in evolving acute myocardial infarction by
granulocyte colony-stimulating factor).
Neuroprotective therapy using
granulocyte colony-stimulating factor for acute spinal cord injury: a phase I/IIa clinical trial.
Dense dosing is made possible by prophylactic administration of
granulocyte colony-stimulating factor (filgrastim) to prevent severe neutropenia.
30 September 2010 - Israeli Teva Pharmaceutical Industries Limited (TLV: TEVA) said today it has received a Complete Response letter from the US Food and Drug Administration (FDA) for the Biologic License Application (BLA) for Neutroval (
granulocyte colony-stimulating factor) for the reduction in the duration of severe neutropenia and the incidence of febrile neutropenia in patients treated with established myelosuppressive chemotherapy for cancer.
2 February 2010 - Israel-based pharmaceutical company Teva Pharmaceutical Industries Ltd (TLV: TEVA) said today that the US Food and Drug Administration (FDA) has accepted for filing Biologics License Application (BLA) for XM02, a
granulocyte colony-stimulating factor (G-CSF) for the reduction in the duration of severe neutropenia and the incidence of febrile neutropenia in patients treated with established myelosuppressive chemotherapy for cancer.
1 December 2009 - Israel-based pharmaceutical company Teva Pharmaceutical Industries Limited (NASDAQ: TEVA) said today it has submitted a Biologics License Application (BLA) to the US Food and Drug Administration (FDA) for XM02, a
granulocyte colony-stimulating factor (G-CSF) for the reduction in the duration of severe neutropenia and the incidence of febrile neutropenia in patients treated with established myelosuppressive chemotherapy for cancer.
Rolontisis a long-acting
granulocyte colony-stimulating factor (G-CSF) being studied as a treatment for neutropenia in patients undergoing myelosuppressive cytotoxic chemotherapy.
In December 2018, the company announced topline data showing that SCLC patients receiving trilaciclib + topotecan experienced statistically significant reductions in the duration and occurrence of Grade 4 neutropenia, and that trilaciclib treatment resulted in a reduction in the number of
granulocyte colony-stimulating factor administrations and red blood cell transfusions, compared to patients receiving placebo + topotecan.
Naturally occurring and therapy-induced antibodies to human
granulocyte colony-stimulating factor (G-CSF) in human serum.