As a result of this enzyme inhibition, telomeres were damaged, resulting in
cancer cell death when p16 levels were low or absent.
Infecting
cancer cells with viruses could increase the effectiveness of conventional chemotherapy, scientists at the University of Birmingham have discovered.
The Texas researchers compared the expression of RLIP76 in normal cells and several
cancer cell lines to explore potential clinical impacts.
These compounds probably do not work directly on the
cancer cell, but through the body's immune system, by stimulating white blood cell activity and retarding growth enzymes in or around the tumor.
Michael White, Associate Professor of Cell Biology at the University of Texas Southwestern Medical Center, explains: "We got the surprise that this mechanism is involved in
cancer cell survival, even though it is normally involved in immune response.
Further, autophagy, process of cellular self-digestion, has been demonstrated to promote
cancer cell survival and drug resistance, but on the other hand it may function as a tumour suppressor mechanism [7].
Pharmaceutical company Adamis Pharmaceuticals Corporation (OTCBB:ADMP.ob) said on Thursday that its drug APC-300 significantly inhibits the growth of pancreatic
cancer cells, in addition to its activity in prostate cancer.
All three extracts inhibited human
cancer cell growth in a dose-dependent manner.
A single tumor-suppressing gene is a key to understanding--and perhaps killing--dormant ovarian
cancer cells that hide out after initial treatment, only to reawaken years later, report researchers at the University of Texas M.D.
Triggered by as-yet-unrecognized signals, the
cancer cells can resume unchecked growth in their new homes and then spread farther, notes Wells' Pittsburgh colleague, Christopher R.
On the basis of these observations, we reasoned that the MCF-7 human breast
cancer cell proliferation (the E-Screen) assay (Soto et al.
Unless every
cancer cell is destroyed, there is always the possibility that the disease will recur.