Symptoms such as urticaria and
anaphylactoid reactions do not stem from true allergic reactions as one would expect after ingesting food or other immune-system-provoking substance.
All iron replacement products have potential life-threatening
anaphylactoid reactions (e.g., hypotension, dyspnea, flushing, and back pain), with iron dextran having the highest risk as compared to the other iron preparations (Fishbane & Shah, 2015; KDIGO Anemia Work Group.
was diagnosed with "vaccine adverse reaction with secondary fever, angioedema, and
anaphylactoid reaction," and admitted for "further treatment and observation." LaLonde, 2012 U.S.
No control skin tests were carried out and, on the basis of the patient's lack of previous exposure and non-elevated serum IgE levels, an
anaphylactoid reaction caused by liberated histamine seemed likely.
These reactions were reviewed by a clinical allergist and were determined to be consistent with anaphylactic or
anaphylactoid reaction.
But she was suddenly hit by an
anaphylactoid reaction - a rapid allergic reaction which can affect multiple parts of the body.
* Special Considerations: Urticaria, angioedema, bronchospasm, and shock might signal an allergic or
anaphylactoid reaction. In clinical trials, the most common localized reactions with Synera among 1,449 patients were erythema (71%), blanching (12%), and edema (12%).
Whenever mast cell mediator release occurs by a direct, non-IgE- mediated process, the term
anaphylactoid reaction should be used.
Immediate hypersensitivity can be divided into three types or syndromes: allergy, anaphylaxis, and
anaphylactoid reaction. The mechanism of action for allergy and anaphylaxis is the same.
Five patients discontinued due to depression, 2 due to marked asymptomatic rises in liver transaminases, 2 due to injection site reactions, 2 due to flu-like symptoms, and 6 for other reasons (lymphopenia,
anaphylactoid reaction, colon cancer, palpitation, psychological disturbance, septicemia).
Perno (1988), "Contact Urticaria and
Anaphylactoid Reaction from Cornstarch Glove Powder," Contact Dermatitis, 19:61-78.