Rasmussen et al., "Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with
transforming growth factor [beta]," The Biochemical Journal, vol.
Transforming growth factor alpha (TGF-alpha) and other targets of tumor necrosis factor-alpha converting enzyme (TACE) in murine polycystic kidney disease.
Connective tissue growth factor induction by lysophosphatidic acid requires transactivation of
transforming growth factor type beta receptors and the JNK pathway.
Transforming growth factor AY effects on osteoclast differentiation via direct and indirect actions J Bone Min Res 2001; 16: 1787-94.
Park, "Mutational analysis of the
transforming growth factor [beta] receptor type II gene in hereditary nonpolyposis colorectal cancer and early-onset colorectal cancer patients," Clinical Cancer Research, vol.
There is an accumulation of ECM in the lamina cribrosa (LC) and trabecular meshwork (TM) and upregulation of profibrotic factors such as
transforming growth factor [beta] (TGF[beta]), collagen1[alpha]1 (COL1A1), and [alpha]-smooth muscle actin ([alpha]SMA).
Mohan, "Role of
transforming growth factor beta in corneal function, biology and pathology," Current Molecular Medicine, vol.
Noble, "
Transforming growth factor in tissue fibrosis," The New England Journal of Medicine, vol.
GDF-15 is a member of the
transforming growth factor [beta] superfamily; it is also known as macrophage inhibitory cytokine-1, placental transforming growth factor-[beta], gene placental bone morphogenic protein, prostate-derived factor, NSAID (nonsteroidal antiinflammatory drug)-activated gene 1, and placental transforming growth factor-[beta].
To test this, LX-2 cells were treated with TCDD in both the absence and presence of
transforming growth factor beta (TGF-[beta]) to induce fibrogenesis or the pro-inflammatory cytokine interleukin-1 beta (IL-1[beta]).
Transforming growth factor [beta]1 (TGF-[beta]1) is implicated in the regulation of cell proliferation, differentiation, and migration, as well as extracellular matrix (ECM) production, apoptosis and tumorigenesis [1].