Loss of chromosomes 9 and 11 may be recurrent chromosome imbalances in
juxtaglomerular cell tumors.
Pathological diagnosis was
juxtaglomerular cell tumor, malignant.
MacLennan, "
Juxtaglomerular cell tumor of the kidney," Journal of Urology, vol.
Juxtaglomerular cell tumor of the kidney: report of two cases with a papillary pattern.
Cascade of RAS starts with the secretion of renin from the
juxtaglomerular cells in the kidneys.
Renin is secreted by the
juxtaglomerular cells of the kidney in response to decreased renal blood flow.
([1]) In response to a decrease in arterial blood pressure, the proteolytic enzyme renin releases from the
juxtaglomerular cells in the kidney and acts on its inactive substrate angiotensinogen (Ang) to form the decapeptide Ang I.
Targeted vitamin D receptor expression in
juxtaglomerular cells suppresses renin expression independent of parathyroid hormone and calcium.