Cycle

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Cycle

References in periodicals archive ?
Based on Acucela's core technology, visual cycle modulation, ACU-4429 is designed as an oral investigational therapy to stop vision loss in dry age-related macular degeneration patients.
The Phase 1a clinical results, presented at ARVO, Aegean Retina XI and ISOPT and published in the journal Retina, demonstrated that ACU-4429 was safe and tolerable in healthy volunteers aged 55-80; and dose-dependent modulation of the visual cycle was shown in electroretinography (ERG) measurement, an eye test used to detect abnormal function of the retina (the light-detecting portion of the eye).
com) is a clinical-stage specialty pharmaceutical company focused on leveraging promising science in visual cycle modulation (VCM) to develop new methods for treating blinding eye diseases that affect tens of millions of people worldwide.
The authors concluded that visual cycle modulation resulted in altered rod function and in enhanced recovery of retinal vessels in OIR.
We look forward to providing an update on our Visual Cycle Modulator (VCM) technology, including ACU-4429, which just entered Phase 2 clinical trials, and discussing our clinical efforts to develop innovative treatments to prevent vision loss.
to co-develop ACU-4429, the company's novel visual cycle modulator (VCM), in dry age-related macular degeneration (dry AMD) as well as other potential indications in North America.
ACU-4429 Slows the Visual Cycle and Represents New Approach to Treating Leading Cause of Blindness in People Over 50; No Therapy Currently Approved