Then, during the past 10 years, the newest technology employing chemiluminescence detection (CLIA) brought more sensitive TSH assays
that accurately detect concentrations as low as 0.
also discuss the ability of heterophilic antibodies to interfere in thyroid hormone and TSH assays
The National Academy of Clinical Biochemistry has recommended that the functional sensitivity of TSH assays
be [less than or equal to]0.
In conclusion, interference from heterophilic antibodies in TSH assays
has become exceptional but still exists (14-16).
Free hormone levels are less reliable measures of thyroid function than are TSH assays
because they are more susceptible to factors that can adversely affect test accuracy.
The test for thyrotropin-releasing hormone (TRH) has been almost completely replaced by more preferred immunoradiometric and other supersensitive TSH assays
who also saw false increases using the Beckman Coulter hCG, TnI, CK-MB and TSH assays
on the Unicel DxI, found reductions in erroneous increases using rapid serum tubes (RSTs) compared to PSTs (1).
Even with "third generation" immunometric TSH assays
, it is important to correlate findings with clinical evaluation of the patient.
But really good TSH assays
were not available until about 10 years ago, so some patients were overtreated and therefore are at risk for significant bone loss.
TSH complexes with IgG may be very rare or may go unidentified because of low reactivity in TSH assays
In this study, we aimed at defining the feasibility of harmonizing TSH assays
by use of new calibrators independent of the current IRPs.
The Whickham survey, performed in the northeastern part of England at a time when no sensitive TSH assays
were available, found thyrotoxicosis in 1.