Connors suggested the lytic capabilities for intraarterial thrombolysis with reteplase
and alteplase are about equal, and the optimal infusion concentrations should be about 1 U reteplase
/100 cc normal saline infused at 0.
About 60% of patients received streptokinase, 27% received reteplase
, and the remaining patients received other agents.
The purpose of this study was to assess the results of the routine use reteplase
for prehospital myocardial infarction in a county with a significant rural population.
But the value of adding reviparin or a similar agent remains in doubt when patients are treated with the fibrin-specific drugs typically used for thrombolysis in the United States, such as alteplase (tissue plasminogen activator), reteplase
, and tenecteplase.
Published reports to date exclusively used streptokinase, urokinase, reteplase
, or recombinant tissue plasminogen activator (t-PA).
BRAVE was an open-label multicenter trial involving 253 German acute MI patients randomized to half-dose reteplase
plus full-dose abciximab or to abciximab alone during the interval between diagnosis and transfer to a cardiac catheterization lab for PCI.
Addition of ReoPro, a Platelet Inhibitor, to the Clot Busting Drug, Reteplase
, is Effective in Breaking Up Difficult Clots Without Increasing Complications