Depression

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Related to Respiratory depression: respiratory failure, Respiratory Distress

Depression

Period when excess aggregate supply overwhelms aggregate demand, resulting in falling prices, unemployment problems, and economic contraction.

Depression

A particularly long and/or deep recession. While there is no technical definition of a depression, conventionally it is defined as a period featuring severe declines in productivity and investment and particularly high unemployment. During the Great Depression, for example, GDP in the United States dropped 12% between 1929 and 1930 and a further 16% the following year. Likewise, unemployment rose to more than 25% nationwide and higher in some places.

Depression.

A depression is a severe and prolonged downturn in the economy. Prices fall, reducing purchasing power. There tends to be high unemployment, lower productivity, shrinking wages, and general economic pessimism.

Since the Great Depression following the stock market crash of 1929, the governments and central banks of industrialized countries have carefully monitored their economies. They adjust their economic policies to try to prevent another financial crisis of this magnitude.

depression

see BUSINESS CYCLE.

depression

a phase of the BUSINESS CYCLE characterized by a severe decline (slump) in the level of economic activity (ACTUAL GROSS NATIONAL PRODUCT). Real output and INVESTMENT are at very low levels and there is a high rate of UNEMPLOYMENT. A depression is caused mainly by a fall in AGGREGATE DEMAND and can be reversed provided that the authorities evoke expansionary FISCAL POLICY and MONETARY POLICY. See DEFLATIONARY GAP, DEMAND MANAGEMENT.
References in periodicals archive ?
Monitor such patients for signs of sedation and respiratory depression, particularly when initiating therapy with BELBUCA(TM).
Although respiratory depression due to epidural morphine is measurably dose-related (22) and low doses of morphine appear to have minimal potential for respiratory depression, the risk of unexpected bulk cerebrospinal flow from lumbar to brainstem with unpredictable delayed respiratory depression with potentially catastrophic outcome has dampened enthusiasm for the technique in many centres.
However, the incidence of respiratory depression in their study was 3%, which many would not regard as low.
The concomitant use of CNS depressants can increase the risk of hypotension, respiratory depression, profound sedation, coma, and death.
While opioid use is generally safe for most patients, opioid analgesics may be associated with adverse effects, the most serious effect being respiratory depression, which is generally preceded by sedation.
3 Anesthesia Patient Safety Foundation Consensus Conference Report: Essential Monitoring Strategies to Detect Clinically Significant Drug-Induced Respiratory Depression in the Postoperative Period, Anesthesia & Analgesia, April 2012, Vol 114, Number 4, The International Anesthesia Research Society
Because of the potential for respiratory depression, caution should be exercised when TUZISTRA XR is administered, including when used postoperatively, in patients with pulmonary disease or shortness of breath, or whenever ventilator function is depressed.
Respiratory Depression Therapeutics under Development by Companies
Morphine sulfate oral solution 100 mg per 5 mL (20 mg/mL) may cause fatal respiratory depression when administered to patients not previously exposed to opioids.
Schedule II opioid substances, which include morphine, oxycodone, hydromorphone, oxymorphone, and methadone, have the highest potential for abuse and risk of fatal overdose due to respiratory depression.
One defines a new composition-of-matter patent, while the other protects our ability to use these compounds for the treatment of opioid-induced respiratory depression and other related breathing disorders for which no approved oral medication exists.
Early indication of respiratory depression with capnography enables medical staff to intervene before serious adverse events happen.

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