A novel mutation on the potassium channel
gene KVLQT1 causes the Jervell and Lange-Nielsen cardioauditory syndrome.
Also, medications that block potassium channels
have been shown to temporarily improve some neurological symptoms.
Since potassium channel
closure may cause membrane depolarization, it is possible that voltage-gated calcium channels are activated during this process and participate in mediating settlement and metamorphosis.
Several types of potassium channels
have been identified in the myometrium, mainly including the large conductance calcium- and voltage-sensitive K [sup]+ channel (BKCa channel), the ATP-sensitive K [sup]+ channel, voltage-gated potassium channels
(Kvs), and small-conductance calcium-sensitive potassium channels
Gross, "Bimakalim, an ATP-sensitive potassium channel
opener, mimics the effects of ischemic preconditioning to reduce infarct size, adenosine release, and neutrophil function in dogs," Circulation, vol.
To determine the possible vasorelaxant mechanism exerted by test sample we used cholinergic antagonist, potassium channel
blocker and enzymatic inhibitors in endothelium signaling pathways throughout rat aorta ring assay.
MacKinnon and his colleagues finally circumvented that obstacle by binding an antibody to each of the four subunits that make up a voltage-dependent potassium channel
Nitric oxide has the ability to initiate the activation of the cGMP-PKG pathway to induce hyperpolarization of vSMCs by modulating the ultrastructure of a calcium-sensitive and ATP-dependent potassium channel
or by decreasing the [Ca.
Cedars-Sinai Medical Center (Los Angeles, CA) has patented a method of inducing apoptosis of a malignant cell, which employs a calcium-activated potassium channel
activator and is useful for treating a malignant tumor in a human subject.
The candidate genes involve a potassium channel
, intra- and intercell-signaling molecules, enzymes that convert propeptides to biologically active peptides, phospholipid-signaling pathways, regulatory and developmental genes that could alter brain development and/or adult form and function, cell adhesion molecules and their possible ligands, as well as those that encode proteins with unknown function.
3 potassium channel
protein in T and B lymphocytes, and detection of related proteins in flies and yeast.
Tedisamil is a nonselective potassium channel
blocker with relative atrial selectivity Although data from just-completed randomized trials of intravenous tedisamil for acute AF are still being analyzed, there is reason for optimism that this drug causes less QT prolongation and has less possibility of potentially fatal torsades de pointes than current antiarrhythmics.