The data suggested that AMG 706 has promising antitumor activity in thyroid cancer, with three patients achieving a partial response
Valero reported that 18 patients (55 percent) achieved partial responses
to Taxotere(R), a highly significant result for a potentially difficult-to-treat patient population.
One patient had a complete response, 19 patients had partial responses
, and one patient had stable disease.
Ten patients had a partial response
in which the size or number of lesions were reduced by at least half.
Of the patients evaluated for radiological response, one patient achieved a partial response
for six months and two patients achieved stable disease for six months.
Of the 10 patients that are evaluable for response, one patient with follicular grade III disease has had a partial response
Three other patients in the group showed partial responses
7%) have demonstrated a clinical response to treatment, including one complete response and two partial responses
Four patients achieved partial responses
, three of which remain durable at 10, 18 and 31 weeks.