cell

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Related to NK cells: T cells, MHC, Macrophages

cell

an independent team of operatives who work together in a CELLULAR MANUFACTURING production environment.
References in periodicals archive ?
Feldan Therapeutics can use its platform to deliver CRISPR nucleases and edit the genome of human NK cells.
In conjunction, the collaboration combines both breakthrough technologies to develop next generations of specific and hyperactive off-the-shelf NK cells for allogeneic immuno-oncology therapies.
NK cells engineered with chimeric antigen receptors can be targeted to tumors with high specificity.
It is known that peripheral blood NK cells are phenotypically and functionally different from endometrial NK cells, with less than 10% resembling endometrial NK cells and differing in surface antigen expression.
Specifically, the investigators identified that approximately 60% of the AML patients who had received treatment with Ceplene/IL-2 harbored NK cells that were potentially reactive with the patient's leukemic cells.
Previous studies have revealed a destructive action of the NK cells on pancreatic islet beta cells and their significant involvement in the development of the disease.
Methods: A case control study was performed comparing the serum levels of VEGF-A and its receptor VEGF-R1 with levels of NK cells, activated NK cells and NK cytotoxicity in 62 women with Repeated Implantation Failure (RIF).
2 Primary mediator of tissue damage being excessive cytokine production by macrophages, NK cells, and CTLs.
Both companies will work together on the generation and evaluation of up to two bispecific NK cell engagers, using technology from Innate Pharma and Sanofi's proprietary bispecific antibody format as well as tumor targets.
The effect of EVs is directly related to their molecular composition and several studies have ascribed an immunostimulatory effect of EVs to the presence of a very specific molecular content [20, 23, 25-31]; for instance, CD56-positive and perforin-containing EVs from NK cells can mediate EV-induced cytotoxicity [20].
In this study, we examined peripheral levels of Treg and NK cells in stage I nonsmall cell lung cancer (NSCLC) patients undergoing lobectomy by VATS or thoracotomy, to disclose perioperative fluctuation of Treg and NK, as well as the correlation between surgical invasiveness and postoperative cell-mediated immune functions.