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Low-Grade
(redirected from Indolent lymphoma)

   Also found in: Dictionary/thesaurus, Medical, Legal, Encyclopedia 0.01 sec.
low-grade
Of or relating to debt that has a credit rating of B or below. Low-grade debt offers an above-average yield but entails substantial risk because promised payments may not be made in a timely manner.

Low-Grade
A bond with a low rating. Bonds rated less than Baa3 by Moody's or BBB- by S&P or Fitch are considered low-grade bonds. They have higher yields than other bonds because they have a higher risk of default on the part of the issuer. Low-grade bonds are considered sufficiently high-risk that the law does not allow banks to invest in them. They are also called high-yield bonds and, informally, junk bonds.


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Non-Hodgkin's lymphomas can be divided clinically into two general categories: indolent lymphomas, mainly typified as follicular lymphomas, that tend to grow relatively slowly, and aggressive lymphomas, mainly typified as DLBCL, which grow more rapidly.
Indolent lymphoma is a slow-growing, incurable disease in which the average patient survives between six and 10 years, following numerous periods of remission and relapse.
We also have developed other potential clinical trial protocols to treat sub-populations of NHL patients, such as those with indolent lymphoma who have not been previously treated with chemotherapy, and may also move forward with these trials, which may allow even faster assessment of the clinical efficacy of our vaccine.
 
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