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The researchers also noted that COX2 and HB-EGF, which prime breast cancer cells for entrance into the brain, had previously been found to be involved in breast cancer's spread to the lung.
Professor of Medicine, Division of Infectious Diseases, at the Baltimore VA Hospital and the University of Maryland, Baltimore, has demonstrated the potential of HB-EGF and APF in the development of a novel interstitial cystitis therapy.
These discoveries could lead to agents which will suppress the production of APF or enhance the production of HB-EGF, both resulting in the formation of a healthy bladder lining.