Commonly Observed Adverse Reactions: The most common adverse reactions (incidence [greater than or equal to] 5%, in either dose group, and at least twice the rate of placebo) in patients treated with LATUDA were akathisia, extrapyramidal symptoms
, somnolence, nausea, vomiting, diarrhea, and anxiety.
Children and adolescents may be particularly vulnerable to antipsychotic adverse effects, including extrapyramidal symptoms
, sedation, weight gain, and prolactin elevation.
Weight gain, drowsiness, extrapyramidal symptoms
(EPS) and dyskinesias, and increased prolactin levels are the most concerning side effects.
It is clear that complaints of visual disturbances in patients taking any of the medications mentioned in the above discussion should be taken seriously and evaluated further for manifestation of other extrapyramidal symptoms
as well as consideration of oculogyric crisis.
Commonly Observed Adverse Beactions: The most common adverse reactions (incidence [greater than or equal to] 5% and at least twice the rate of placebo) in patients treated with LATUDA were somnolence, akathisia, extrapyramidal symptoms
, and nausea.
After three months of treatment her symptoms were completely under control so her maintenance dosage was reduced to olanzapine 15 mg/d and her trihexphenidyl was subsequently stopped because her extrapyramidal symptoms
29, 2008, identified 69 cases of neonatal extrapyramidal symptoms
(EPS) or withdrawal associated with different antipsychotics, with symptoms that varied in severity.
The rate of extrapyramidal symptoms
was 24% among those on ziprasidone, compared with almost 8% among placebo.
Extrapyramidal side effects were rated using the rating scale for extrapyramidal symptoms
(ESRS) (18) and the abnormal involuntary movement scale (AIMS) (19).
Antipsychotics work primarily by blocking dopamine neurotransmission in the brain, but dopamine blockade is also related to side effects called extrapyramidal symptoms
5 mg) are useful but have side effects including se dation, hyperprolactinemia, type 2 diabetes, and extrapyramidal symptoms
Additionally, there does not appear to be the increase in prolactin or extrapyramidal symptoms
which are usually associated with the Lise of typical neuroleptics.