Studies have found that DES daughters are more likely to suffer from ectopic pregnancies, miscarriages and infertility problems.
One question that's difficult to answer is whether the problem of recurrent miscarriages in DES daughters - and now granddaughters - would be genetic or due to the drug, said Dr.
Unfortunately, the structure of DES differs just enough from estrogen that those protective proteins can't grasp the drug.
Since the maturation of the female reproductive tract occurs in response to estrogen, it's not surprising that DES interferes with this process.
In these experiments, BPA was found to be 5,000 times less active than DES in activating ER-[alpha] and 1,400 times less active than DES toward ER-[beta] transactivation.
We successfully applied our new sensitive estrogen reporter mice to assess the ability of DES, EP, and BPA to activate ER signaling in embryos.
But that said, Sherins argues that even in the face of this new DES
study, "you have to be cautious about putting the whole [reproductive] issue of environmental estrogens to rest.
DES inspected over 300 abandoned mines in the Timmins District of, Northern Ontario to provide detailed site assessments that include GPS data of the site, detailed descriptions-and estimated costs to rehabilitate,
DES performs all long-term monitoring at both sites.