FAS

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Related to CD95: Fas protein, Fas ligand

FAS

Abbreviation for the Incoterm Free Alongside Ship.

Free Alongside Ship

In maritime, international commerce, an agreement between a buyer (importer) and a seller (exporter) in which the seller is responsible for the transportation and risk of the good until it is within reach of the ship's crane, at which point the buyer assumes responsibility for both. That is, the seller does not bear the expense or risk of actually loading the good onto the ship. The buyer is responsible for clearing the good through customs in both the home country and the country of delivery.
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These data raised the intriguing possibility that CD95 could actually promote the growth of tumours," said lead author Marcus Peter of Northwestern University.
Activation of the CD95 system increases with disease progression in human immunodeficiency virus type 1-infected children and adolescents.
Since the CD95 ligand is expressed in many types of cancer, there is tremendous potential for the use of APG101.
These findings indicate that a genetic predisposition to an increased expression of CD95 may help to protect from severe malaria, possibly by rendering a type of white blood cell more susceptible to programmed cell death.
It is also observed that the highly active antiretroviral therapy in HIV infected individuals can decrease the CD95 expression on naive T cells (18).
In the phase II trial, glioblastoma patients expressing a certain biomarker associated with the CD95 ligand experienced the greatest benefit from treatment with APG101.
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).
323) Although CD95 (FAS) is uniformly expressed in LyP and C-ALCL, (324) inhibition of this pathway may also be secondary to upregulation of c-FLIP.
Phosphatidylinositol 3'-kinase blocks CD95 aggregation and caspase-8 cleavage at the death-inducing signaling complex by modulating lateral diffusion of CD95.
Similarly, other proteins involved in apoptosis, such as bc1-2, bax, CD95, or specific caspases, cannot currently be used for determining sensitivity or resistance to anticancer treatments [for a review, see Ref.
The data demonstrates that treatment with APG101, a CD95 ligand-binding fusion protein, in combination with radiotherapy is an innovative concept that has shown clinical superiority in all study endpoints compared to treatment with radiotherapy alone.
Trans-cinnamaldehyde is partially effective through up-regulation of CD95 (Zhang et al.