loss

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Related to Bone loss: osteopenia

Loss

The opposite of gain.

Loss

Extracting less money from a transaction than one put into it. For example, a business' expenses may be $1 million for a year but it may only take in $800,000 in revenue. In such a case, the business has suffered a $200,000 loss. This is not always bad; most businesses lose money in the first few years of operation and this can reduce their tax liability when they do make a profit. However, losses over an extended period of time ultimately result in failure. See also: Gain, Paper Loss, Loss Carryforward, Loss Carryback.

loss

The deficiency of the amount received as opposed to the amount invested in a transaction. Compare gain. See also net loss.

loss

the shortfall between a firm's sales revenues received from the sale of its products and the total costs incurred in producing the firm's output (see BREAK-EVEN ANALYSIS). Losses may be of a temporary nature occasioned by, for example, a downturn in demand (see BUSINESS CYCLE) or due to an exceptional level of expenditures (such as the launch of a series of new products). Short-term losses are usually financed by a firm running down its RESERVES or by an increase in borrowings. Losses which are sustained over time typically arise from a firm's poor competitive position in a market (see COMPETITIVE ADVANTAGE), and unless competitiveness can be restored market exit or DIVESTMENT may be the only practical way of remedying the situation. See MARKET SYSTEM.

loss

the difference that arises when a firm's TOTAL REVENUES are less than TOTAL COSTS. In the SHORT RUN, where firms’ total revenues are insufficient to cover VARIABLE COSTS, then they will exit from the market unless they perceive this situation as being temporary. In these circumstances, where firms’ total revenues are sufficient to cover variable costs and make some CONTRIBUTION towards FIXED COSTS, then they will continue to produce despite overall losses. In the LONG RUN, however, unless firms’ revenues are sufficient to cover both variable and fixed costs, then their overall losses will cause them to exit from the market. See MARKET EXIT, LOSS MINIMIZATION, PROFIT-AND-LOSS ACCOUNT.
References in periodicals archive ?
If bone loss continues in this population, however, the risk of fractures later in life might be increased.
ACE-011 is being jointly developed by Acceleron and Celgene Corporation for the treatment of cancer-related bone loss.
Data from the current study suggest that bone loss may be arrested by intra-articular corticosteroid injections more effectively in periarticular regions than in the whole hand," the researchers wrote.
These data provide evidence that inflammatory processes may be involved in some of the adaptation to microgravity and suggest that reducing NFI*B activation could serve as a countermeasure to bone loss.
Average Rates of Trabecular and Cortical Bone Loss per Year Rate in Rate in Fast Losers Slow Losers Trabecular bone of radius 6.
With the help of treadmill exercise countermeasure, the research team was able to prevent bone loss in important skeletal regions.
At 1-year follow-up, only baseline FSH level was significantly related to bone loss.
While GILZ is induced by glucocorticoids, directly overexpressing the protein appears to better target sources of bone loss and inflammation and avoid these serious side effects.
In this study, researchers first determined whether mice that were induced with experimental arthritis also manifested bone loss in the alveolar (tooth socket) bone.
The long term consequences of this substantial bone loss are unclear but it might put them at increased risk of fracture or breaking a bone," said Elaine Yu, endocrinologist at Massachusetts General Hospital, Boston in the US.
In women, due to the normal process of aging and loss of oestrogen, normal bone loss takes place; in women smokers, bone loss is more rapid.
Understanding bone loss associated with microgravity can help researchers understand the mechanisms of bone loss in a wide range of disorders.